Regenerative medicine is the "process of replacing or regenerating human cells, tissues or organs to restore or establish normal function with own or laboratory made cells/tissues. Regenerative Medicine has been a long practice in the form of Bone Marrow Transplantation for cancers and bone grafting for orthopedic applications etc. These innovative medical therapies are showing great promise over traditional medical treatment in terms of safety and efficacy.
How Regenerative Medicine Helps in Healing?
Stem cells originate from locations called stem cell niche to repair the damaged part of specific organ. When stem cell niche is unable to provide sufficient stem cells, Bone Marrow will mobilize stem cells to the damaged site. In certain cases, the bone marrow may not mobilize stem cells due to lack of signals from degenerative site, dysfunction of circulatory system (i.e Peripheral artery disease/Diabetic foot) or mobilized cells may not be sufficient to cure the degenerative area. Therefore we devise technologies to transfer cell or tissue from other healthy areas of the body i.e. Bone grafting, skin grafting etc. Once stem cells are placed in degeneration area, Bone marrow stem cells will be converted to particular organ cells with the help of the microenvironment of the organs.
What to expect from regenerative medicine presently
The regenerative medicine have been providing solutions for many “lost hope” patients and improving their quality of life. As mentioned before, the regenerative medicine therapeutic protocols are individualized unlike drugs. At present, the regenerative medicine will not promise in organ creation and replacement. However the therapy improves the quality of life for the patients to lead their normal life who exhausted with existing medical treatment.
After concluding that the regenerative therapies are safe and effective, number of patients with debilitating diseases are obtaining the treatment and leading the better quality of life. However, regenerative medicine is not a solution for each and every therapeutic aspect. Usually stem cells also will not perform well in some sort of end stage diseases due to complete death / necrosis of tissue or cells
Note: Cytocare is a provider of processing technologies and services for regenerative and transfusion medicine applications. Some of the regenerative medicine products may be used in clinical trials only.
Pure Platelet Rich Plasma for Orthopedic Applications
PRP is blood plasma that has been enriched with platelets. As a concentrated source of autologous platelets, PRP contains several different growth factors and other cytokines that stimulate healing.
Osteoarthritis (OA) is a degenerative disease of the connective tissue and progresses with age in the older population or develops in young athletes following sports-related injury. The articular cartilage is especially vulnerable to damage and has poor potential for regeneration because of the absence of vasculature within the tissue. Osteoarthritis of the knee is caused by the physical deterioration of the cartilage and underlying bone in the knee joint, resulting in stiffness, swelling, pain and difficulty in walking
Platelet-rich plasma (PRP) therapy involves injecting patient’s own concentrated blood components (platelets) into their knee(s). The aim is to promote cartilage repair and relieve symptoms like pain and functional disability.
- Best cost effective technology.
- Simple Point of care technology.
- Intra operative support.
- Can separate Adipose tissue from Lipoaspirate in 15 min for treatment.
- Can prepare SVF from Lipoaspirate in 30 mins.
- Evidence based therapeutic protocols and technology.
- ADSC proven efficacy in various indications.
- Compatible with any centrifuges.
- Minimum steps required.
- Easy separation with only one KIT.
- Separation/isolation can be done with only one time of centrifugation.
- Closed system / No air contamination possibility.
- Gamma irradiation of device ensures no microbial contamination.
- No chemical additives.
- Single use disposable kit.
- Helps in separation of patients own ADSCs from lipoaspirate based on simple density gradient system using centrifuge.
- One system for various indications which require Stem cell therapy.